Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes.

Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes.

Preservation of β-cell function as measured by stimulated C-peptide has recently been accepted as a therapeutic target for subjects with newly diagnosed type 1 diabetes. In recently completed studies conducted by the Type 1 Diabetes Trial Network (TrialNet), repeated 2-hour Mixed Meal Tolerance Test...

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Bibliographic Details
Main Authors: John M Lachin, Paula L McGee, Carla J Greenbaum, Jerry Palmer, Mark D Pescovitz, Peter Gottlieb, Jay Skyler, Type 1 Diabetes Trial Network
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3213096?pdf=render

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http://europepmc.org/articles/PMC3213096?pdf=render

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