Metabolic Disorder, Inflammation, and Deregulated Molecular Pathways Converging in Pancreatic Cancer Development: Implications for New Therapeutic Strategies

Metabolic Disorder, Inflammation, and Deregulated Molecular Pathways Converging in Pancreatic Cancer Development: Implications for New Therapeutic Strategies

Pancreatic cancer develops and progresses through complex, cumulative biological processes involving metabolic disorder, local inflammation, and deregulated molecular pathways. The resulting tumor aggressiveness hampers surgical intervention and renders pancreatic cancer resistant to standard chemot...

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Bibliographic Details
Main Authors: Toshinari Minamoto, Kazuyuki Kawakami, Hideo Nakajima, Takeo Shimasaki, Yasuhito Ishigaki, Yoshiharu Motoo
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Cancers
Subjects:
pancreatic cancer
glucose intolerance
inflammation
oncogenic pathways
therapeutic target
GSK3β
Online Access:http://www.mdpi.com/2072-6694/3/1/446/

Internet

http://www.mdpi.com/2072-6694/3/1/446/

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