The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

The initial interaction between a microbial pathogen and the host immune response influences the outcome of the battle between the host and the foreign invader. Leprosy, caused by the obligate intracellular pathogen Mycobacterium leprae, provides a model to study relevant human immune responses. Pre...

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Bibliographic Details
Main Authors: Priscila R Andrade, Manali Mehta, Jing Lu, Rosane M B Teles, Dennis Montoya, Phillip O Scumpia, Euzenir Nunes Sarno, Maria Teresa Ochoa, Feiyang Ma, Matteo Pellegrini, Robert L Modlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007589

Internet

https://doi.org/10.1371/journal.pntd.0007589

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