The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy

The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a common cause of end-stage renal disease. Evaluation of a kidney biopsy is necessary for diagnosis, with routine immunofluorescence microscopy revealing dominant or co-dominant IgA immunodeposits usually with...

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Bibliographic Details
Main Authors: Dana V. Rizk, Nicolas Maillard, Bruce A. Julian, Barbora Knoppova, Todd J. Green, Jan Novak, Robert J. Wyatt
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
complement
IgA nephropathy
alternative complement pathway
mannan binding lectin complement pathway
IgAN pathogenesis
IgAN
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00504/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00504/full

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