Mitoxantrone-Induced Suicidal Erythrocyte Death

Mitoxantrone-Induced Suicidal Erythrocyte Death

Background/Aims: Mitoxantrone, a cytotoxic drug used for the treatment of malignancy and multiple sclerosis, is at least in part effective by triggering apoptosis. Similar to apoptosis of nucleated cells, erythrocytes may enter eryptosis, a type of suicidal cell death. Hallmarks of eryptosis are cel...

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Bibliographic Details
Main Authors: Markus Arnold, Rosi Bissinger, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Phosphatidylserine
Mitoxantrone
Calcium
Ceramide
Cell volume
Eryptosis
Online Access:http://www.karger.com/Article/FullText/366376

Internet

http://www.karger.com/Article/FullText/366376

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