Roles of Tristetraprolin in Tumorigenesis

Roles of Tristetraprolin in Tumorigenesis

Genetic loss or mutations in tumor suppressor genes promote tumorigenesis. The prospective tumor suppressor tristetraprolin (TTP) has been shown to negatively regulate tumorigenesis through destabilizing the messenger RNAs of critical genes implicated in both tumor onset and tumor progression. Regul...

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Bibliographic Details
Main Authors: Jeong-Min Park, Tae-Hee Lee, Tae-Hong Kang
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
tristetraprolin (TTP)
tumorigenesis
posttranscriptional regulation
adenosine and uridine-rich elements (AREs)
Online Access:https://www.mdpi.com/1422-0067/19/11/3384

Internet

https://www.mdpi.com/1422-0067/19/11/3384

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