Neutrophil extracellular traps and bacterial biofilms in middle ear effusion of children with recurrent acute otitis media--a potential treatment target.

BACKGROUND: Bacteria persist within biofilms on the middle ear mucosa of children with recurrent and chronic otitis media however the mechanisms by which these develop remain to be elucidated. Biopsies can be difficult to obtain from children and their small size limits analysis. METHODS: In this st...

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Bibliographic Details
Main Authors: Ruth B Thornton, Selma P Wiertsema, Lea-Ann S Kirkham, Paul J Rigby, Shyan Vijayasekaran, Harvey L Coates, Peter C Richmond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3564866?pdf=render