Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.

Novel strategies that target the epidermal growth factor receptor (EGFR) have led to the clinical development of monoclonal antibodies, which treat metastatic colorectal cancer (mCRC) but only subgroups of patients with increased wild type KRAS and EGFR gene copy, respond to these agents. Furthermor...

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Bibliographic Details
Main Authors: Gadi Cohen, Shimon Lecht, Hadar Arien-Zakay, Keren Ettinger, Orit Amsalem, Mor Oron-Herman, Eylon Yavin, Diana Prus, Simon Benita, Aviram Nissan, Philip Lazarovici
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3493605?pdf=render