Age and sex specific effects of APOE genotypes on ischemic heart disease and its risk factors in the UK Biobank

Abstract APOE genotypes are associated with ischemic heart disease (IHD), several other cardiovascular diseases and dementia. Previous studies have not comprehensively considered all genotypes, especially ε2ε2, nor associations by age and sex, although IHD incidence differs by sex. In the UK Biobank...

Full description

Bibliographic Details
Main Authors: Mengyu Li, Jie V. Zhao, Man Ki Kwok, C. Mary Schooling
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88256-x