Markers of nitric oxide are associated with sepsis severity: an observational study

Abstract Background Nitric oxide (NO) regulates processes involved in sepsis progression, including vascular function and pathogen defense. Direct NO measurement in patients is unfeasible because of its short half-life. Surrogate markers for NO bioavailability are substrates of NO generating synthas...

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Main Authors: Martin Sebastian Winkler, Stefan Kluge, Maximilian Holzmann, Eileen Moritz, Linda Robbe, Antonia Bauer, Corinne Zahrte, Marion Priefler, Edzard Schwedhelm, Rainer H. Böger, Alwin E. Goetz, Axel Nierhaus, Christian Zoellner
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-017-1782-2