Fatal Dengue Cases Reveal Brain Injury and Viral Replication in Brain-Resident Cells Associated with the Local Production of Pro-Inflammatory Mediators

Fatal Dengue Cases Reveal Brain Injury and Viral Replication in Brain-Resident Cells Associated with the Local Production of Pro-Inflammatory Mediators

Dengue is an arboviral disease caused by dengue virus (DENV), which is transmitted to humans by <i>Aedes aegypti</i> mosquitoes. Infection by DENV most commonly results in a mild flu-like illness; however, the disease has been increasingly associated with neurological symptomatology. Thi...

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Bibliographic Details
Main Authors: Natália Salomão, Kíssila Rabelo, Carlos Basílio-de-Oliveira, Rodrigo Basílio-de-Oliveira, Luiz Geraldo, Flávia Lima, Flávia dos Santos, Gerard Nuovo, Edson R. A. Oliveira, Marciano Paes
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
dengue
human fatal cases
neuropathogenesis
inflammation
central nervous system
Online Access:https://www.mdpi.com/1999-4915/12/6/603

Internet

https://www.mdpi.com/1999-4915/12/6/603

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