Analysis of T4SS-induced signaling by H. pylori using quantitative phosphoproteomics

Analysis of T4SS-induced signaling by H. pylori using quantitative phosphoproteomics

Helicobacter pylori is a Gram-negative bacterial pathogen colonizing the human stomach. Infection with H. pylori causes chronic inflammation of the gastric mucosa and may lead to peptic ulceration and/or gastric cancer. A major virulence determinant of H. pylori is the type IV secretion system (T4SS...

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Bibliographic Details
Main Authors: Frithjof eGlowinski, Carsten eHolland, Bernd eThiede, Peter Roman Jungblut, Thomas F Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Microbiology
Subjects:
phosphoproteomics
SILAC
T4SS
CagA
tyrosine signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00356/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00356/full

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