Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist.

Cancer stem cells (CSCs) have increased resistance to cancer chemotherapy. They can be enriched as drug-surviving CSCs (D-CSCs) by growth with chemotherapeutic drugs, and/or by sorting of cells expressing CSC markers such as aldehyde dehydrogenase-1 (ALDH). CSCs form colonies in agar, mammospheres i...

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Bibliographic Details
Main Authors: Gérald J Prud'homme, Yelena Glinka, Anna Toulina, Olga Ace, Venkateswaran Subramaniam, Serge Jothy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2972222?pdf=render