Single nucleotide polymorphisms of Toll-like receptor 4 decrease the risk of development of hepatocellular carcinoma.

BACKGROUND: Toll-like receptor 4 (TLR4) is a key innate immunity receptor that initiates an inflammatory response. Growing evidence suggests that mutation of TLR4 gene may play a role in the development of cancers. This study aimed to investigate the temporal relationship of single nucleotide polymo...

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Bibliographic Details
Main Authors: Shi Minmin, Xu Xiaoqian, Chen Hao, Shen Baiyong, Deng Xiaxing, Xie Junjie, Zhan Xi, Zhao Jianquan, Jiang Songyao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084862?pdf=render