Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence
<p>Abstract</p> <p>Background</p> <p>To understand the evolutionary steps required for a virus to become virulent in a new host, a human influenza A virus (IAV), A/Hong Kong/1/68(H3N2) (HK-wt), was adapted to increased virulence in the mouse. Among eleven mutations sele...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-01-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/8/1/13 |