Low polymorphisms in pfact, pfugt and pfcarl genes in African Plasmodium falciparum isolates and absence of association with susceptibility to common anti-malarial drugs

Low polymorphisms in pfact, pfugt and pfcarl genes in African Plasmodium falciparum isolates and absence of association with susceptibility to common anti-malarial drugs

Abstract Background Resistance to all available anti-malarial drugs has emerged and spread including artemisinin derivatives and their partner drugs. Several genes involved in artemisinin and partner drugs resistance, such as pfcrt, pfmdr1, pfK13 or pfpm2, have been identified. However, these genes...

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Bibliographic Details
Main Authors: Francis Tsombeng Foguim, Marie Gladys Robert, Mamadou Wagué Gueye, Mathieu Gendrot, Silman Diawara, Joel Mosnier, Rémy Amalvict, Nicolas Benoit, Raymond Bercion, Bécaye Fall, Marylin Madamet, Bruno Pradines, The French National Reference Centre for Imported Malaria Study Group
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Anti-malarial drug
In vitro
Resistance
Molecular marker
Online Access:http://link.springer.com/article/10.1186/s12936-019-2919-3

Internet

http://link.springer.com/article/10.1186/s12936-019-2919-3

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