The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70

The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70

Manipulating cell cycle is one of the common strategies used by viruses to generate favorable cellular environment to facilitate viral replication. Coxsackievirus B (CVB) is one of the major viral pathogens of human myocarditis and cardiomyopathy. Because of its small genome, CVB depends on cellular...

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Bibliographic Details
Main Authors: Yao Wang, Shuoxuan Zhao, Yang Chen, Tianying Wang, Chaorun Dong, Xiaoman Wo, Jian Zhang, Yanyan Dong, Weizhen Xu, Xiaofeng Feng, Cong Qu, Yan Wang, Zhaohua Zhong, Wenran Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
coxsackievirus B
capsid protein VP1
cell cycle
G1 arrest
heat shock protein 70
heat shock factor 1
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01633/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01633/full

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