YAP enhances autophagic flux to promote breast cancer cell survival in response to nutrient deprivation.

The Yes-associated protein (YAP), a transcriptional coactivator inactivated by the Hippo tumor suppressor pathway, functions as an oncoprotein in a variety of cancers. However, its contribution to breast cancer remains controversial. This study investigated the role of YAP in breast cancer cells und...

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Bibliographic Details
Main Authors: Qinghe Song, Beibei Mao, Jinbo Cheng, Yuhao Gao, Ke Jiang, Jun Chen, Zengqiang Yuan, Songshu Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374846?pdf=render