Combining Sodium Butyrate With Cisplatin Increases the Apoptosis of Gastric Cancer In Vivo and In Vitro via the Mitochondrial Apoptosis Pathway

Combining Sodium Butyrate With Cisplatin Increases the Apoptosis of Gastric Cancer In Vivo and In Vitro via the Mitochondrial Apoptosis Pathway

Introduction: The gastrointestinal malignancy, gastric cancer (GC), has a high incidence worldwide. Cisplatin is a traditional chemotherapeutic drug that is generally applied to treat cancer; however, drug tolerance affects its efficacy. Sodium butyrate is an intestinal flora derivative that has gen...

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Bibliographic Details
Main Authors: Yangbo Li, Pengzhan He, Yinghui Liu, Mingming Qi, Weiguo Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
sodium butyrate
cisplatin
gastric cancer
apoptosis
mitochondrial pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.708093/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.708093/full

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