Phylogenetic analysis of the SINA/SIAH ubiquitin E3 ligase family in Metazoa

Phylogenetic analysis of the SINA/SIAH ubiquitin E3 ligase family in Metazoa

Abstract Background The RAS signaling pathway is a pivotal developmental pathway that controls many fundamental biological processes including cell proliferation, differentiation, movement and apoptosis. Drosophila Seven-IN-Absentia (SINA) is a ubiquitin E3 ligase that is the most downstream signali...

Full description

Bibliographic Details
Main Authors: Ian J. Pepper, Robert E. Van Sciver, Amy H. Tang
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Evolutionary Biology
Subjects:
RAS signal transduction
SINA/SIAH E3 ligases
Ubiquitin-mediated proteolysis
Phylogenetic analysis
Invariant and divergent amino acid residues
And conserved functional domains in SINA
Online Access:http://link.springer.com/article/10.1186/s12862-017-1024-x

Internet

http://link.springer.com/article/10.1186/s12862-017-1024-x

Similar Items