Heritable CRISPR/Cas9-mediated genome editing in the yellow fever mosquito, Aedes aegypti.

Heritable CRISPR/Cas9-mediated genome editing in the yellow fever mosquito, Aedes aegypti.

In vivo targeted gene disruption is a powerful tool to study gene function. Thus far, two tools for genome editing in Aedes aegypti have been applied, zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN). As a promising alternative to ZFN and TALEN, which are diffi...

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Bibliographic Details
Main Authors: Shengzhang Dong, Jingyi Lin, Nicole L Held, Rollie J Clem, A Lorena Passarelli, Alexander W E Franz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376861?pdf=render

Internet

http://europepmc.org/articles/PMC4376861?pdf=render

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