Patchouli alcohol attenuates 5-fluorouracil-induced intestinal mucositis via TLR2/MyD88/NF-kB pathway and regulation of microbiota

Patchouli alcohol attenuates 5-fluorouracil-induced intestinal mucositis via TLR2/MyD88/NF-kB pathway and regulation of microbiota

Intestinal mucositis causes great suffering to cancer patients who undergo chemotherapy and radiotherapy. Owing to the uncertain side effects of anticancer drugs to attenuate patients’ intestinal mucositis, many studies focused on traditional Chinese medicine (TCM). Patchouli alcohol (PA) is an acti...

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Bibliographic Details
Main Authors: Jiazhen Wu, Yuxuan Gan, Muxia Li, Liping Chen, Jiali Liang, Jianyi Zhuo, Huijuan Luo, Nan Xu, Xue Wu, Qiduan Wu, Zhixiu Lin, Ziren Su, Yuhong Liu
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Patchouli alcohol
Intestinal mucositis
Inflammation
Mucosal barrier
Intestinal microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220300731

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220300731

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