Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer

Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer

Abstract Background The search for molecular biomarkers of early-onset colorectal cancer (CRC) is an important but still quite challenging and unsolved task. Detection of CpG methylation in human DNA obtained from blood or stool has been proposed as a promising approach to a noninvasive early diagno...

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Bibliographic Details
Main Authors: Alexander Kel, Ulyana Boyarskikh, Philip Stegmaier, Leonid S. Leskov, Andrey V. Sokolov, Ivan Yevshin, Nikita Mandrik, Daria Stelmashenko, Jeannette Koschmann, Olga Kel-Margoulis, Mathias Krull, Anna Martínez-Cardús, Sebastian Moran, Manel Esteller, Fedor Kolpakov, Maxim Filipenko, Edgar Wingender
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Bioinformatics
Subjects:
Prognostic biomarkers
Colorectal cancer
Multi-omics analysis
DNA methylation
Circulating DNA
Transcription factor binding sites
Online Access:http://link.springer.com/article/10.1186/s12859-019-2687-7

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http://link.springer.com/article/10.1186/s12859-019-2687-7

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