Molecular and Functional Diversity of Distinct Subpopulations of the Stressed Insulin-Secreting Cell's Vesiculome

Molecular and Functional Diversity of Distinct Subpopulations of the Stressed Insulin-Secreting Cell's Vesiculome

Beta cell failure and apoptosis following islet inflammation have been associated with autoimmune type 1 diabetes pathogenesis. As conveyors of biological active material, extracellular vesicles (EV) act as mediators in communication with immune effectors fostering the idea that EV from inflamed bet...

Full description

Bibliographic Details
Main Authors: Khem Raj Giri, Laurence de Beaurepaire, Dominique Jegou, Margot Lavy, Mathilde Mosser, Aurelien Dupont, Romain Fleurisson, Laurence Dubreil, Mayeul Collot, Peter Van Endert, Jean-Marie Bach, Gregoire Mignot, Steffi Bosch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
type 1 diabetes
extracellular vesicles
apoptotic bodies
microvesicles
exosomes
microRNA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01814/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01814/full

Similar Items