Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening

Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening

To advance pre-clinical vascular drug research, <i>in vitro</i> assays are needed that closely mimic the process of angiogenesis <i>in vivo</i>. Such assays should combine physiological relevant culture conditions with robustness and scalability to enable drug screening. We d...

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Bibliographic Details
Main Authors: Vincent van Duinen, Wendy Stam, Eva Mulder, Farbod Famili, Arie Reijerkerk, Paul Vulto, Thomas Hankemeier, Anton Jan van Zonneveld
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
angiogenesis
drug screening
microfluidics
iPSC
endothelial cells
Online Access:https://www.mdpi.com/1422-0067/21/13/4804

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https://www.mdpi.com/1422-0067/21/13/4804

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