Short RNA guides cleavage by eukaryotic RNase III.

In eukaryotes, short RNAs guide a variety of enzymatic activities that range from RNA editing to translation repression. It is hypothesized that pre-existing proteins evolved to bind and use guide RNA during evolution. However, the capacity of modern proteins to adopt new RNA guides has never been d...

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Bibliographic Details
Main Authors: Bruno Lamontagne, Sherif Abou Elela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000472