Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese.

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese.

In Asia, young-onset type 2 diabetes (YOD) is characterized by obesity and increased risk for cardiovascular disease (CVD). In a genome-wide association study (GWAS) of 99 Chinese obese subjects with familial YOD diagnosed before 40-year-old and 101 controls, the T allele of rs1408888 in intron 1 of...

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Main Authors: Ronald Ching Wan Ma, Heung Man Lee, Vincent Kwok Lim Lam, Claudia Ha Ting Tam, Janice Siu Ka Ho, Hai-Lu Zhao, Jing Guan, Alice Pik Shan Kong, Eric Lau, Guozhi Zhang, Andrea Luk, Ying Wang, Stephen Kwok Wing Tsui, Ting Fung Chan, Cheng Hu, Wei Ping Jia, Kyong Soo Park, Hong Kyu Lee, Hiroto Furuta, Kishio Nanjo, E Shyong Tai, Daniel Peng-Keat Ng, Nelson Leung Sang Tang, Jean Woo, Ping Chung Leung, Hong Xue, Jeffrey Wong, Po Sing Leung, Terrence C K Lau, Peter Chun Yip Tong, Gang Xu, Maggie Chor Yin Ng, Wing Yee So, Juliana Chung Ngor Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3896349?pdf=render

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http://europepmc.org/articles/PMC3896349?pdf=render

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