Anxa2 attenuates osteoblast growth and is associated with hip BMD and osteoporotic fracture in Chinese elderly.

Low bone mineral density (BMD) is a risk factor of osteoporotic fracture (OF). Peripheral blood monocytes (PBM) can differentiate into osteoclasts to resorb bone. It was known that PBM-expressed Anxa2 protein is associated with BMD, and extracellular Anxa2 protein promotes osteoclastogenesis. This s...

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Bibliographic Details
Main Authors: Xu Zhou, Long-Fei Wu, Wen-Yu Wang, Xin Lu, Zhen-Huan Jiang, Yun-Hong Zhang, Ding-Hua Jiang, Jian-Nong Jiang, Hong-Qing Gao, Shu-Feng Lei, Fei-Yan Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5865729?pdf=render