Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM?

Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM?

Despite recent advances in tumor imaging and chemoradiotherapy, the median overall survival of patients diagnosed with glioblastoma multiforme does not exceed 15 months. Infiltration of glioma cells into the brain parenchyma, and the blood-brain barrier are important hurdles to further increase the...

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Bibliographic Details
Main Authors: Stefaan W. van Gool, Steven de Vleeschouwer, Florence Lefranc, Véronique Mathieu, Rémi Rosière, Karim Amighi, Matthias van Woensel, Nathalie Wauthoz
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Cancers
Subjects:
glioblastoma multiforme
intranasal administration
nose-to-brain delivery
formulations
nanoparticles
drug delivery
new therapy concept
Online Access:http://www.mdpi.com/2072-6694/5/3/1020

Internet

http://www.mdpi.com/2072-6694/5/3/1020

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