On the discovery of a potential survivin inhibitor combining computational tools and cytotoxicity studies

Survivin protein is a metalloprotein member of the inhibitors of apoptosis proteins family, involved in the regulation of programmed cell death. Due to the recent development of antitumor therapies having survivin as molecular target, several strategies to interfere with the expression or function o...

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Bibliographic Details
Main Authors: Patricia A. Quispe, Martin J. Lavecchia, Ignacio E. León
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019358980