The bacterial protein CNF1 as a new strategy against Plasmodium falciparum cytoadherence.

Plasmodium falciparum severe malaria causes more than 400,000 deaths every year. One feature of P. falciparum-parasitized erythrocytes (pRBC) leading to cerebral malaria (CM), the most dangerous form of severe malaria, is cytoadherence to endothelium and blockage of the brain microvasculature. Preve...

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Bibliographic Details
Main Authors: Valeria Messina, Stefano Loizzo, Sara Travaglione, Lucia Bertuccini, Maria Condello, Fabiana Superti, Marco Guidotti, Pietro Alano, Francesco Silvestrini, Carla Fiorentini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213529