Polyphenolic Fraction Obtained From Thalassia testudinum Marine Plant and Thalassiolin B Exert Cytotoxic Effects in Colorectal Cancer Cells and Arrest Tumor Progression in a Xenograft Mouse Model

Polyphenolic Fraction Obtained From Thalassia testudinum Marine Plant and Thalassiolin B Exert Cytotoxic Effects in Colorectal Cancer Cells and Arrest Tumor Progression in a Xenograft Mouse Model

Marine plants are important sources of pharmacologically active metabolites. The aim of the present work was to evaluate the cytotoxic and antitumor activity of a polyphenolic fraction obtained from Thalassia testudinum marine plant and thalassiolin B in human colorectal cancer cells. Human cancer c...

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Bibliographic Details
Main Authors: Livan Delgado-Roche, Kethia González, Fernando Mesta, Beatriz Couder, Zaira Tavarez, Ruby Zavala, Ivones Hernandez, Gabino Garrido, Idania Rodeiro, Wim Vanden Berghe
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
T. testudinum
polyphenols
thalassiolin B
colorectal cancer
reactive oxygen species
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.592985/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.592985/full

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