Role of Diffusion Tensor Imaging in Prognostication and Treatment Monitoring in Niemann-Pick Disease Type C1

Role of Diffusion Tensor Imaging in Prognostication and Treatment Monitoring in Niemann-Pick Disease Type C1

Niemann-Pick Disease, type C1 (NPC1) is a rapidly progressive neurodegenerative disorder characterized by cholesterol sequestration within late endosomes and lysosomes, for which no reliable imaging marker exists for prognostication and management. Cerebellar volume deficits are found to correlate w...

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Bibliographic Details
Main Authors: Meghann W. Lau, Ryan W. Lee, Robin Miyamoto, Eun Sol Jung, Nicole Yanjanin Farhat, Shoko Yoshida, Susumu Mori, Andrea Gropman, Eva H. Baker, Forbes D. Porter
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Diseases
Subjects:
Niemann-Pick
NPC
diffusion tensor imaging
DTI
cerebellum
motor function
Online Access:http://www.mdpi.com/2079-9721/4/3/29

Internet

http://www.mdpi.com/2079-9721/4/3/29

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