Calpastatin-Mediated Inhibition of Calpain Ameliorates Skin Scar Formation after Burn Injury

Calpastatin-Mediated Inhibition of Calpain Ameliorates Skin Scar Formation after Burn Injury

Hypertrophic scars, the most common complication of burn injuries, are characterized by excessive deposition of fibroblast-derived extracellular matrix proteins. Calpain, a calcium-dependent protease, is involved in the fibroblast proliferation and extracellular matrix production observed in certain...

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Bibliographic Details
Main Authors: Cheong Hoon Seo, Hui Song Cui, June-Bum Kim
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
wound
hypertrophy
complication
Online Access:https://www.mdpi.com/1422-0067/22/11/5771

Internet

https://www.mdpi.com/1422-0067/22/11/5771

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