Current Status of Targeted Therapy for Anaplastic Lymphoma Kinase in Non-small Cell Lung Cancer

The rate of the anaplastic lymphoma kinase (ALK) gene rearrangements in non-small cell lung cancer (NSCLC) tissues is 3%-5%. The first-in-class ALK tyrosine kinase inhibitor, crizotinib, can effectively target these tumors represent a significant advance in the evolution of personalized medicine for...

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Bibliographic Details
Main Authors: Li MA, Shucai ZHANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2014-12-01
Series:Chinese Journal of Lung Cancer
Subjects:
ALK
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2014.12.05