Efficient Neutrophil Activation Requires Two Simultaneous Activating Stimuli

Efficient Neutrophil Activation Requires Two Simultaneous Activating Stimuli

Neutrophils are abundantly present in the synovium and synovial fluid of patients suffering from arthritis. Neutrophils can be activated by a multitude of stimuli and the current dogma states that this is a two-step process, consisting of a priming step followed by an activation step. Considering th...

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Bibliographic Details
Main Authors: Sanne Mol, Florianne M. J. Hafkamp, Laura Varela, Neena Simkhada, Esther W. Taanman-Kueter, Sander W. Tas, Marca H. M. Wauben, Tom Groot Kormelink, Esther C. de Jong
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
degranulation
mediator release
ROS production
NETosis
phagocytosis
extracellular vesicle release
Online Access:https://www.mdpi.com/1422-0067/22/18/10106

Internet

https://www.mdpi.com/1422-0067/22/18/10106

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