Two-step Synthesis of Solasodine Pivalate from Diosgenin Pivalate
A two-step synthesis of solasodine pivalate from diosgenin pivalate is described. The key transformation involves the reaction of diosgenin pivalate with benzyl carbamate (CbzNH<sub>2</sub>) promoted by TMSOTf. During the reaction the F-ring of the spiroketal moiety opens up with a simul...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/24/6/1132 |