The Exosomal/Total α-Synuclein Ratio in Plasma Is Associated With Glucocerebrosidase Activity and Correlates With Measures of Disease Severity in PD Patients

The Exosomal/Total α-Synuclein Ratio in Plasma Is Associated With Glucocerebrosidase Activity and Correlates With Measures of Disease Severity in PD Patients

Intensive research efforts in the field of Parkinson’s disease (PD) are focusing on identifying reliable biomarkers which possibly help physicians in predicting disease onset, diagnosis, and progression as well as evaluating the response to disease-modifying treatments. Given that abnormal alpha-syn...

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Bibliographic Details
Main Authors: Silvia Cerri, Cristina Ghezzi, Maria Sampieri, Francesca Siani, Micol Avenali, Gianluca Dornini, Roberta Zangaglia, Brigida Minafra, Fabio Blandini
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
α-synuclein
glucocerebrosidase
exosomes
biomarkers
Parkinson’s disease
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00125/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00125/full

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