Gli as a novel therapeutic target in malignant pleural mesothelioma.

Gli as a novel therapeutic target in malignant pleural mesothelioma.

Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis. Current treatment is rarely curative, thus novel meaningful therapies are urgently needed. Inhibition of Hedgehog (Hh) signaling at the cell membrane level in several cancers has shown anti-cancer activity in rece...

Full description

Bibliographic Details
Main Authors: Hui Li, Natalie Lui, Tiffany Cheng, Hsin-Hui K Tseng, Dongsheng Yue, Etienne Giroux-Leprieur, Hanh T Do, Qing Sheng, Joy Q Jin, Thomas W Luh, David M Jablons, Biao He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590216?pdf=render

Internet

http://europepmc.org/articles/PMC3590216?pdf=render

Similar Items