A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation.

A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation.

OBJECTIVES:Previous small animal models for simulation of mechanical unloading are solely performed in healthy or infarcted hearts, not representing the pathophysiology of hypertrophic and dilated hearts emerging in heart failure patients. In this article, we present a new and economic small animal...

Full description

Bibliographic Details
Main Authors: Andreas Schaefer, Yvonne Schneeberger, Justus Stenzig, Daniel Biermann, Marisa Jelinek, Hermann Reichenspurner, Thomas Eschenhagen, Heimo Ehmke, Alexander P Schwoerer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4739720?pdf=render

Internet

http://europepmc.org/articles/PMC4739720?pdf=render

Similar Items