Transverse tubule remodeling enhances Orai1-dependent Ca2+ entry in skeletal muscle

Transverse tubule remodeling enhances Orai1-dependent Ca2+ entry in skeletal muscle

Exercise promotes the formation of intracellular junctions in skeletal muscle between stacks of sarcoplasmic reticulum (SR) cisternae and extensions of transverse-tubules (TT) that increase co-localization of proteins required for store-operated Ca2+ entry (SOCE). Here, we report that SOCE, peak Ca2...

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Bibliographic Details
Main Authors: Antonio Michelucci, Simona Boncompagni, Laura Pietrangelo, Maricela García-Castañeda, Takahiro Takano, Sundeep Malik, Robert T Dirksen, Feliciano Protasi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
calcium signaling
skeletal muscle
store operated calcium entry
Orai1 channels
Online Access:https://elifesciences.org/articles/47576

Internet

https://elifesciences.org/articles/47576

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