Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity

A pathological hallmark of Parkinson’s disease (PD) is formation of Lewy bodies in neurons of the brain. This has been attributed to the spread of α-synuclein (α-syn) aggregates, which involves release of α-syn from a neuron and its reuptake by a neighboring neuron. We found that treatment with plas...

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Bibliographic Details
Main Authors: Peng Wang, Xin Li, Xuran Li, Weiwei Yang, Shun Yu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2016/7596482