A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms

Ketamine is an uncompetitive N-methyl-d-aspartate (NMDA) glutamate receptor antagonist. It induces effects in healthy individuals that mimic symptoms associated with schizophrenia. We sought to root these experiences in altered brain function, specifically aberrant resting state functional connectiv...

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Bibliographic Details
Main Authors: Leah M. Fleming, Daniel C. Javitt, Cameron S. Carter, Joshua T. Kantrowitz, Ragy R. Girgis, Lawrence S. Kegeles, John D. Ragland, Richard J. Maddock, Tyler A. Lesh, Costin Tanase, James Robinson, William Z. Potter, Marlene Carlson, Melanie M. Wall, Tse-Hwei Choo, Jack Grinband, Jeffrey Lieberman, John H. Krystal, Philip R. Corlett
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219300890