Polo-Like Kinase 4 (PLK4) Is Overexpressed in Central Nervous System Neuroblastoma (CNS-NB)

Polo-Like Kinase 4 (PLK4) Is Overexpressed in Central Nervous System Neuroblastoma (CNS-NB)

Neuroblastoma (NB) is the most common extracranial solid tumor in pediatrics, with rare occurrences of primary and metastatic tumors in the central nervous system (CNS). We previously reported the overexpression of the polo-like kinase 4 (PLK4) in embryonal brain tumors. PLK4 has also been found to...

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Bibliographic Details
Main Authors: Anders W. Bailey, Amreena Suri, Pauline M. Chou, Tatiana Pundy, Samantha Gadd, Stacey L. Raimondi, Tadanori Tomita, Simone Treiger Sredni
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Bioengineering
Subjects:
embryonal brain tumor
pediatric
CNS-PNET
low grade glioma
rhabdoid
ATRT
medulloblastoma
kinase inhibitor
Online Access:https://www.mdpi.com/2306-5354/5/4/96

Internet

https://www.mdpi.com/2306-5354/5/4/96

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