Potassium bisperoxo (1,10-phenanthroline) oxovanadate suppresses proliferation of hippocampal neuronal cell lines by increasing DNA methyltransferases

Potassium bisperoxo (1,10-phenanthroline) oxovanadate suppresses proliferation of hippocampal neuronal cell lines by increasing DNA methyltransferases

Bisperoxo (1,10-phenanthroline) oxovanadate (BpV) can reportedly block the cell cycle. The present study examined whether BpV alters gene expression by affecting DNA methyltransferases (DNMTs), which would impact the cell cycle. Immortalized mouse hippocampal neuronal precursor cells (HT22) were tre...

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Bibliographic Details
Main Authors: Xiao-Li Tian, Shu-Yuan Jiang, Xiao-Lu Zhang, Jie Yang, Jun-He Cui, Xiao-Lei Liu, Ke-Rui Gong, Shao-Chun Yan, Chun-Yang Zhang, Guo Shao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; hippocampal neurons; potassium bisperoxo (1
10-phenanthroline) oxovanadate; DNA methyltransferase; p21; HT22 cell; cell cycle; immunoblotting; DNA methylation; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=5;spage=826;epage=833;aulast=Tian

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=5;spage=826;epage=833;aulast=Tian

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