Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

Hepatitis C virus (HCV) is a highly variable pathogen that frequently establishes chronic infection. This genetic variability is affected by the adaptive immune response but the contribution of other host factors is unclear. Here, we examined the role played by interferon lambda-4 (IFN-λ4) on HCV di...

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Bibliographic Details
Main Authors: M Azim Ansari, Elihu Aranday-Cortes, Camilla LC Ip, Ana da Silva Filipe, Siu Hin Lau, Connor Bamford, David Bonsall, Amy Trebes, Paolo Piazza, Vattipally Sreenu, Vanessa M Cowton, STOP-HCV Consortium, Emma Hudson, Rory Bowden, Arvind H Patel, Graham R Foster, William L Irving, Kosh Agarwal, Emma C Thomson, Peter Simmonds, Paul Klenerman, Chris Holmes, Eleanor Barnes, Chris CA Spencer, John McLauchlan, Vincent Pedergnana
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
hepatitis C virus
genome-to-genome analysis
host-pathogen interactions
interferon lambda 4
innate immunity
Online Access:https://elifesciences.org/articles/42463

Internet

https://elifesciences.org/articles/42463

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