Small-Diameter Subchondral Drilling Improves DNA and Proteoglycan Content of the Cartilaginous Repair Tissue in a Large Animal Model of a Full-Thickness Chondral Defect

Small-Diameter Subchondral Drilling Improves DNA and Proteoglycan Content of the Cartilaginous Repair Tissue in a Large Animal Model of a Full-Thickness Chondral Defect

This study quantified changes in the DNA content and extracellular matrix composition of both the cartilaginous repair tissue and the adjacent cartilage in a large animal model of a chondral defect treated by subchondral drilling. Content of DNA, proteoglycans, and Type II and Type I collagen, as we...

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Bibliographic Details
Main Authors: Patrick Orth, Mona Eldracher, Magali Cucchiarini, Henning Madry
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
articular cartilage
marrow stimulation
subchondral drilling
early osteoarthritis
extracellular matrix
proteoglycan
Online Access:https://www.mdpi.com/2077-0383/9/6/1903

Internet

https://www.mdpi.com/2077-0383/9/6/1903

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