Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells.

Molt-4 leukemia cells undergo p53-dependent apoptosis accompanied by accumulation of de novo ceramide after 14 hours of γ-irradiation. In order to identify the potential mediators involved in ceramide accumulation and the cell death response, differentially expressed genes were identified by Affymet...

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Bibliographic Details
Main Authors: Rouba Hage-Sleiman, Hisham Bahmad, Hadile Kobeissy, Zeinab Dakdouk, Firas Kobeissy, Ghassan Dbaibo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5741252?pdf=render