Targeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilization.

Fibrinogen like protein 1(Fgl1) is a secreted protein with mitogenic activity on primary hepatocytes. Fgl1 is expressed in the liver and its expression is enhanced following acute liver injury. In animals with acute liver failure, administration of recombinant Fgl1 results in decreased mortality sup...

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Bibliographic Details
Main Authors: Valeriy Demchev, Geraldine Malana, Divya Vangala, Janis Stoll, Anal Desai, Hye Won Kang, Yingxia Li, Hamed Nayeb-Hashemi, Michele Niepel, David E Cohen, Chinweike Ukomadu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590190?pdf=render