Influence of the microwave technology on solid dispersions of mefenamic acid and flufenamic acid.

The present studies were undertaken to develop solvent-free solid dispersions (SDs) for poorly soluble anti-inflammatory drugs mefenamic acid (MA) and flufenamic acid (FFA) in order to enhance their in vitro dissolution rate and in vivo anti-inflammatory effects. The SDs of MA and FFA were prepared...

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Main Authors: Sultan Alshehri, Faiyaz Shakeel, Mohamed Ibrahim, Ehab Elzayat, Mohammad Altamimi, Gamal Shazly, Kazi Mohsin, Musaed Alkholief, Bader Alsulays, Abdullah Alshetaili, Abdulaziz Alshahrani, Bander Almalki, Fars Alanazi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5536357?pdf=render